The Subthalamic Nucleus becomes a Generator of Bursts in the Dopamine-Depleted State. Its High Frequency Stimulation Dramatically Weakens Transmission to the Globus Pallidus

Excessive burst firing in the dopamine-depleted basal ganglia correlates with severe motor symptoms of Parkinson's disease that are attenuated by high frequency electrical stimulation of the subthalamic nucleus (STN). Here we test the hypothesis that pathological bursts in dopamine-deprived bas...

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Detalles Bibliográficos
Autores principales: Ammari, Rachida, Bioulac, Bernard, Garcia, Liliana, Hammond, Constance
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115486/
https://www.ncbi.nlm.nih.gov/pubmed/21716635
http://dx.doi.org/10.3389/fnsys.2011.00043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115486/
https://www.ncbi.nlm.nih.gov/pubmed/21716635
http://dx.doi.org/10.3389/fnsys.2011.00043

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