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A.N. Kolmogorov’s defence of Mendelism
In 1939 N.I. Ermolaeva published the results of an experiment which repeated parts of Mendel’s classical experiments. On the basis of her experiment she concluded that Mendel’s principle that self-pollination of hybrid plants gave rise to segregation proportions 3:1 was false. The great probability...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Sociedade Brasileira de Genética
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115669/ https://www.ncbi.nlm.nih.gov/pubmed/21734813 http://dx.doi.org/10.1590/S1415-47572011000200002 |
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author | Stark, Alan Seneta, Eugene |
author_facet | Stark, Alan Seneta, Eugene |
author_sort | Stark, Alan |
collection | PubMed |
description | In 1939 N.I. Ermolaeva published the results of an experiment which repeated parts of Mendel’s classical experiments. On the basis of her experiment she concluded that Mendel’s principle that self-pollination of hybrid plants gave rise to segregation proportions 3:1 was false. The great probability theorist A.N. Kolmogorov reviewed Ermolaeva’s data using a test, now referred to as Kolmogorov’s, or Kolmogorov-Smirnov, test, which he had proposed in 1933. He found, contrary to Ermolaeva, that her results clearly confirmed Mendel’s principle. This paper shows that there were methodological flaws in Kolmogorov’s statistical analysis and presents a substantially adjusted approach, which confirms his conclusions. Some historical commentary on the Lysenko-era background is given, to illuminate the relationship of the disciplines of genetics and statistics in the struggle against the prevailing politically-correct pseudoscience in the Soviet Union. There is a Brazilian connection through the person of Th. Dobzhansky. |
format | Online Article Text |
id | pubmed-3115669 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Sociedade Brasileira de Genética |
record_format | MEDLINE/PubMed |
spelling | pubmed-31156692011-07-06 A.N. Kolmogorov’s defence of Mendelism Stark, Alan Seneta, Eugene Genet Mol Biol Review Article In 1939 N.I. Ermolaeva published the results of an experiment which repeated parts of Mendel’s classical experiments. On the basis of her experiment she concluded that Mendel’s principle that self-pollination of hybrid plants gave rise to segregation proportions 3:1 was false. The great probability theorist A.N. Kolmogorov reviewed Ermolaeva’s data using a test, now referred to as Kolmogorov’s, or Kolmogorov-Smirnov, test, which he had proposed in 1933. He found, contrary to Ermolaeva, that her results clearly confirmed Mendel’s principle. This paper shows that there were methodological flaws in Kolmogorov’s statistical analysis and presents a substantially adjusted approach, which confirms his conclusions. Some historical commentary on the Lysenko-era background is given, to illuminate the relationship of the disciplines of genetics and statistics in the struggle against the prevailing politically-correct pseudoscience in the Soviet Union. There is a Brazilian connection through the person of Th. Dobzhansky. Sociedade Brasileira de Genética 2011-04-01 2011 /pmc/articles/PMC3115669/ /pubmed/21734813 http://dx.doi.org/10.1590/S1415-47572011000200002 Text en Copyright © 2011, Sociedade Brasileira de Genética. Printed in Brazil License information: This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Stark, Alan Seneta, Eugene A.N. Kolmogorov’s defence of Mendelism |
title | A.N. Kolmogorov’s defence of Mendelism |
title_full | A.N. Kolmogorov’s defence of Mendelism |
title_fullStr | A.N. Kolmogorov’s defence of Mendelism |
title_full_unstemmed | A.N. Kolmogorov’s defence of Mendelism |
title_short | A.N. Kolmogorov’s defence of Mendelism |
title_sort | a.n. kolmogorov’s defence of mendelism |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115669/ https://www.ncbi.nlm.nih.gov/pubmed/21734813 http://dx.doi.org/10.1590/S1415-47572011000200002 |
work_keys_str_mv | AT starkalan ankolmogorovsdefenceofmendelism AT senetaeugene ankolmogorovsdefenceofmendelism |