WRB is the receptor for TRC40/Asna1-mediated insertion of tail-anchored proteins into the ER membrane

Tail-anchored (TA) proteins are post-translationally targeted to and inserted into the endoplasmic reticulum (ER) membrane through their single C-terminal transmembrane domain. Membrane insertion of TA proteins in mammalian cells is mediated by the ATPase TRC40/Asna1 (Get3 in yeast) and a receptor i...

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Detalles Bibliográficos
Autores principales: Vilardi, Fabio, Lorenz, Holger, Dobberstein, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Company of Biologists 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115773/
https://www.ncbi.nlm.nih.gov/pubmed/21444755
http://dx.doi.org/10.1242/jcs.084277

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