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Analysis of the Mitogen-activated protein kinase kinase 4 (MAP2K4) tumor suppressor gene in ovarian cancer
BACKGROUND: MAP2K4 is a putative tumor and metastasis suppressor gene frequently found to be deleted in various cancer types. We aimed to conduct a comprehensive analysis of this gene to assess its involvement in ovarian cancer. METHODS: We screened for mutations in MAP2K4 using High Resolution Melt...
Autores principales: | Davis, Sally J, Choong, David YH, Ramakrishna, Manasa, Ryland, Georgina L, Campbell, Ian G, Gorringe, Kylie L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115913/ https://www.ncbi.nlm.nih.gov/pubmed/21575258 http://dx.doi.org/10.1186/1471-2407-11-173 |
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