Cargando…

Genomic Polymorphism of the Pandemic A (H1N1) Influenza Viruses Correlates with Viral Replication, Virulence, and Pathogenicity In Vitro and In Vivo

The novel pandemic A (H1N1) virus was first identified in Mexico in April 2009 and quickly spread worldwide. Like all influenzas, the H1N1 strain-specific properties of replication, virulence, and pathogenicity are a result of the particular genomic sequence and concerted expression of multiple gene...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Lili, Bao, Linlin, Zhou, Jianfang, Wang, Dayan, Deng, Wei, Lv, Qi, Ma, Yila, Li, Fengdi, Sun, Huihui, Zhan, Lingjun, Zhu, Hua, Ma, Chunmei, Shu, Yuelong, Qin, Chuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115934/ https://www.ncbi.nlm.nih.gov/pubmed/21698272 http://dx.doi.org/10.1371/journal.pone.0020698

Ejemplares similares

Correction: Genomic Polymorphism of the Pandemic A (H1N1) Influenza Viruses Correlates with Viral Replication, Virulence, and Pathogenicity In Vitro and In Vivo
por: Xu, Lili, et al.
Publicado: (2020)

A single-amino-acid substitution in the HA protein changes the replication and pathogenicity of the 2009 pandemic A (H1N1) influenza viruses in vitro and in vivo
por: Xu, Lili, et al.
Publicado: (2010)

Adaption of Seasonal H1N1 Influenza Virus in Mice
por: Xu, Lili, et al.
Publicado: (2011)

An Optimized Real-Time PCR to Avoid Species-/Tissue-Associated Inhibition for H5N1 Detection in Ferret and Monkey Tissues
por: Zhan, LingJun, et al.
Publicado: (2012)

Mutations in Polymerase Genes Enhanced the Virulence of 2009 Pandemic H1N1 Influenza Virus in Mice
por: Zhu, Wenfei, et al.
Publicado: (2012)

Substitution of D701N in the PB2 protein could enhance the viral replication and pathogenicity of Eurasian avian-like H1N1 swine influenza viruses
por: Liu, Suli, et al.
Publicado: (2018)

PIAS1-mediated SUMOylation of influenza A virus PB2 restricts viral replication and virulence
por: Wang, Guangwen, et al.
Publicado: (2022)

Acetylation at K108 of the NS1 protein is important for the replication and virulence of influenza virus
por: Ma, Jingjiao, et al.
Publicado: (2020)

Homologous PB1 gene promotes the replication efficiency of avian influenza H7N4 candidate vaccine virus
por: Liu, Liqi, et al.
Publicado: (2022)

Mammalian-adaptive mutation NP-Q357K in Eurasian H1N1 Swine Influenza viruses determines the virulence phenotype in mice
por: Zhu, Wenfei, et al.
Publicado: (2019)

Vγ4(+)γδT Cells Aggravate Severe H1N1 Influenza Virus Infection-Induced Acute Pulmonary Immunopathological Injury via Secreting Interleukin-17A
por: Xue, Chunxue, et al.
Publicado: (2017)

Interleukin-37 Ameliorates Influenza Pneumonia by Attenuating Macrophage Cytokine Production in a MAPK-Dependent Manner
por: Qi, Feifei, et al.
Publicado: (2019)

Human-Derived A/Guangdong/Th005/2017 (H7N9) Exhibits Extremely High Replication in the Lungs of Ferrets and Is Highly Pathogenic in Chickens
por: Gong, Shuran, et al.
Publicado: (2019)

Comparison of the replication and neutralization of different SARS‐CoV‐2 Omicron subvariants in vitro
por: Zhang, Yaqing, et al.
Publicado: (2023)

Neurotropism In Vitro and Mouse Models of Severe and Mild Infection with Clinical Strains of Enterovirus 71
por: Yu, Pin, et al.
Publicado: (2017)

Residues 41V and/or 210D in the NP protein enhance polymerase activities and potential replication of novel influenza (H7N9) viruses at low temperature
por: Zhu, Wenfei, et al.
Publicado: (2015)

Additional Evidence That the Polymerase Subunits Contribute to the Viral Replication and the Virulence of H5N1 Avian Influenza Virus Isolates in Mice
por: Qu, Xiao, et al.
Publicado: (2015)

H1N1 influenza virus dose dependent induction of dysregulated innate immune responses and STAT1/3 activation are associated with pulmonary immunopathological damage
por: Yao, Duoduo, et al.
Publicado: (2022)

Transmission of H7N9 influenza virus in mice by different infective routes
por: Bao, Linlin, et al.
Publicado: (2014)

Correction to: Transmission of H7N9 influenza virus in mice by different infective routes
por: Bao, Linlin, et al.
Publicado: (2021)

Highly pathogenic avian influenza H5N1 virus could partly be evacuated by pregnant BALB/c mouse during abortion or preterm delivery
por: Xu, Lili, et al.
Publicado: (2011)

Suppression of Rac1 Signaling by Influenza A Virus NS1 Facilitates Viral Replication
por: Jiang, Wei, et al.
Publicado: (2016)

Ficolin A exacerbates severe H1N1 influenza virus infection-induced acute lung immunopathological injury via excessive complement activation
por: Wu, Xu, et al.
Publicado: (2021)

DMO-CAP inhibits influenza virus replication by activating heme oxygenase-1-mediated IFN response
por: Zhong, Ming, et al.
Publicado: (2019)

Hemagglutinin stem reactive antibody response in individuals immunized with a seasonal influenza trivalent vaccine
por: Zhao, Xiaopeng, et al.
Publicado: (2015)

Viral-induced alternative splicing of host genes promotes influenza replication
por: Thompson, Matthew G, et al.
Publicado: (2020)

220 mutation in the hemagglutinin of avian influenza A (H7N9) virus alters antigenicity during vaccine strain development
por: Liu, Liqi, et al.
Publicado: (2018)

The Ablation of Envelope Protein Glycosylation Enhances the Neurovirulence of ZIKV and Cell Apoptosis in Newborn Mice
por: Guo, Yanqing, et al.
Publicado: (2021)

Annexin A2 (ANXA2) interacts with nonstructural protein 1 and promotes the replication of highly pathogenic H5N1 avian influenza virus
por: Ma, Yong, et al.
Publicado: (2017)

Naturally occurring mutations in PB1 affect influenza A virus replication fidelity, virulence, and adaptability
por: Lin, Ruey-Wen, et al.
Publicado: (2019)

Influenza A Virus (H1N1) Infection Induces Glycolysis to Facilitate Viral Replication
por: Ren, Lehao, et al.
Publicado: (2021)

Antigenic Patterns and Evolution of the Human Influenza A (H1N1) Virus
por: Liu, Mi, et al.
Publicado: (2015)

Characteristics of oseltamivir-resistant influenza A (H1N1) pdm09 virus during the 2013–2014 influenza season in Mainland China
por: Huang, Weijuan, et al.
Publicado: (2015)

Diverse biological characteristics and varied virulence of H7N9 from Wave 5
por: Bao, Linlin, et al.
Publicado: (2019)

A single N342D substitution in Influenza B Virus NA protein determines viral pathogenicity in mice
por: Zhou, Lijuan, et al.
Publicado: (2020)

Sequential infection with H1N1 and SARS-CoV-2 aggravated COVID-19 pathogenesis in a mammalian model, and co-vaccination as an effective method of prevention of COVID-19 and influenza
por: Bao, Linlin, et al.
Publicado: (2021)

Delayed oseltamivir plus sirolimus treatment attenuates H1N1 virus-induced severe lung injury correlated with repressed NLRP3 inflammasome activation and inflammatory cell infiltration
por: Jia, Xuehong, et al.
Publicado: (2018)

Epidemiological and Genetic Characteristics of the H3 Subtype Avian Influenza Viruses in China
por: Yang, Jiaying, et al.
Publicado: (2021)

Whole Genome and Transcriptome Sequencing of Two Multi-Drug Resistant Mycobacterium tuberculosis Strains to Facilitate Illustrating Their Virulence in vivo
por: Tang, Jun, et al.
Publicado: (2020)

Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus
por: Hale, Benjamin G., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_sh10f2s2jo6s8ujm6kjnsjas1v