In Vitro Megakaryocyte Differentiation and Proplatelet Formation in Ph-Negative Classical Myeloproliferative Neoplasms: Distinct Patterns in the Different Clinical Phenotypes

BACKGROUND: Ph-negative myeloproliferative neoplasms (MPNs) are clonal disorders that include primary myelofibrosis (PMF), polycythemia vera (PV) and essential thrombocythemia (ET). Although the pathogenesis of MPNs is still incompletely understood, an involvement of the megakaryocyte lineage is a d...

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Detalles Bibliográficos
Autores principales: Balduini, Alessandra, Badalucco, Stefania, Pugliano, Maria Teresa, Baev, Denis, De Silvestri, Annalisa, Cattaneo, Marco, Rosti, Vittorio, Barosi, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115954/
https://www.ncbi.nlm.nih.gov/pubmed/21698292
http://dx.doi.org/10.1371/journal.pone.0021015

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