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OSBP-Related Protein 8 (ORP8) Regulates Plasma and Liver Tissue Lipid Levels and Interacts with the Nucleoporin Nup62
We earlier identified OSBP-related protein 8 (ORP8) as an endoplasmic reticulum oxysterol-binding protein implicated in cellular lipid homeostasis. We now investigated its action in hepatic cells in vivo and in vitro. Adenoviral overexpression of ORP8 in mouse liver induced a decrease of cholesterol...
Autores principales: | Zhou, Tianhong, Li, Shiqian, Zhong, Wenbin, Vihervaara, Terhi, Béaslas, Olivier, Perttilä, Julia, Luo, Wei, Jiang, Yingliang, Lehto, Markku, Olkkonen, Vesa M., Yan, Daoguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115989/ https://www.ncbi.nlm.nih.gov/pubmed/21698267 http://dx.doi.org/10.1371/journal.pone.0021078 |
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