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Cutaneous denervation of psoriasiform mouse skin improves acanthosis and inflammation in a sensory neuropeptide dependent manner
Nervous system involvement in psoriasis pathogenesis is supported by increases in nerve fiber numbers and neuropeptides in psoriatic skin and by reports detailing spontaneous plaque remission following nerve injury. Using the KC-Tie2 psoriasisform mouse model, we investigated the mechanisms by which...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116081/ https://www.ncbi.nlm.nih.gov/pubmed/21471984 http://dx.doi.org/10.1038/jid.2011.60 |