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Dynamic Expression of Notch Signaling Genes in Neural Stem/Progenitor Cells

In neural stem/progenitor cells, expression of the Notch effector Hes1, a transcriptional repressor, oscillates with a period of 2–3 h by negative feedback, and Hes1 oscillations induce the oscillatory expression of the proneural gene Neurogenin2 (Ngn2) and the Notch ligand gene Delta-like1 (Dll1)....

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Detalles Bibliográficos
Autores principales:	Shimojo, Hiromi, Ohtsuka, Toshiyuki, Kageyama, Ryoichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2011
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116140/ https://www.ncbi.nlm.nih.gov/pubmed/21716644 http://dx.doi.org/10.3389/fnins.2011.00078

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