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Investigations on Inhibitors of Hedgehog Signal Pathway: A Quantitative Structure-Activity Relationship Study

The hedgehog signal pathway is an essential agent in developmental patterning, wherein the local concentration of the Hedgehog morphogens directs cellular differentiation and expansion. Furthermore, the Hedgehog pathway has been implicated in tumor/stromal interaction and cancer stem cell. Nowadays...

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Detalles Bibliográficos
Autores principales: Zhu, Ruixin, Liu, Qi, Tang, Jian, Li, Huiliang, Cao, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116172/
https://www.ncbi.nlm.nih.gov/pubmed/21686166
http://dx.doi.org/10.3390/ijms12053018