KRAS Mutation Detection in Paired Frozen and Formalin-Fixed Paraffin-Embedded (FFPE) Colorectal Cancer Tissues

KRAS mutation has been unambiguously identified as a marker of resistance to cetuximab-based treatment in metastatic colorectal cancer (mCRC) patients. However, most studies of KRAS mutation analysis have been performed using homogenously archived CRC specimens, and studies that compare freshly froz...

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Detalles Bibliográficos
Autores principales: Solassol, Jérome, Ramos, Jeanne, Crapez, Evelyne, Saifi, Majda, Mangé, Alain, Vianès, Evelyne, Lamy, Pierre-Jean, Costes, Valérie, Maudelonde, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116185/
https://www.ncbi.nlm.nih.gov/pubmed/21686179
http://dx.doi.org/10.3390/ijms12053191

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