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Optimized alkylated cyclodextrin polysulphates with reduced risks on thromboembolic accidents improve osteoarthritic chondrocyte metabolism

Objectives. To compare the ability of different cyclodextrin polysulphate (CDPS) derivatives to affect human articular cartilage cell metabolism in vitro. Methods. OA chondrocytes were cultured in alginate and exposed to 5 µg/ml of 2,3,6-tri-O-methyl-β-cyclodextrin (ME-CD), 2,3-di-O-methyl-6-sulphat...

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Detalles Bibliográficos
Autores principales:	Groeneboer, Sara, Lambrecht, Stijn, Dhollander, Aad, Jacques, Peggy, Cruyssen, Bert Vander, Lories, Rik J., Devreese, Katrien, Chiers, Koen, Elewaut, Dirk, Verbruggen, Gust
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Basic Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116210/ https://www.ncbi.nlm.nih.gov/pubmed/21345936 http://dx.doi.org/10.1093/rheumatology/keq396

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