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Histone variant macroH2A confers resistance to nuclear reprogramming
How various layers of epigenetic repression restrict somatic cell nuclear reprogramming is poorly understood. The transfer of mammalian somatic cell nuclei into Xenopus oocytes induces transcriptional reprogramming of previously repressed genes. Here, we address the mechanisms that restrict reprogra...
Autores principales: | Pasque, Vincent, Gillich, Astrid, Garrett, Nigel, Gurdon, John B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116279/ https://www.ncbi.nlm.nih.gov/pubmed/21552206 http://dx.doi.org/10.1038/emboj.2011.144 |
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