Cargando…

Box C/D snoRNP catalysed methylation is aided by additional pre-rRNA base-pairing

2′-O-methylation of eukaryotic ribosomal RNA (r)RNA, essential for ribosome function, is catalysed by box C/D small nucleolar (sno)RNPs. The RNA components of these complexes (snoRNAs) contain one or two guide sequences, which, through base-pairing, select the rRNA modification site. Adjacent to the...

Descripción completa

Detalles Bibliográficos
Autores principales: van Nues, Robert Willem, Granneman, Sander, Kudla, Grzegorz, Sloan, Katherine Elizabeth, Chicken, Matthew, Tollervey, David, Watkins, Nicholas James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116282/
https://www.ncbi.nlm.nih.gov/pubmed/21556049
http://dx.doi.org/10.1038/emboj.2011.148