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Itk: The Rheostat of the T Cell Response
The nonreceptor tyrosine kinase Itk plays a key role in TCR-initiated signaling that directly and significantly affects the regulation of PLCγ1 and the consequent mobilization of Ca(2+). Itk also participates in the regulation of cytoskeletal reorganization as well as cellular adhesion, which is nec...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116522/ https://www.ncbi.nlm.nih.gov/pubmed/21747996 http://dx.doi.org/10.1155/2011/297868 |