Examinations of tRNA Range of Motion Using Simulations of Cryo-EM Microscopy and X-Ray Data

We examined tRNA flexibility using a combination of steered and unbiased molecular dynamics simulations. Using Maxwell's demon algorithm, molecular dynamics was used to steer X-ray structure data toward that from an alternative state obtained from cryogenic-electron microscopy density maps. Thu...

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Detalles Bibliográficos
Autores principales: Caulfield, Thomas R., Devkota, Batsal, Rollins, Geoffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116532/
https://www.ncbi.nlm.nih.gov/pubmed/21716650
http://dx.doi.org/10.1155/2011/219515

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