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A distinctive role for focal adhesion proteins in three-dimensional cell motility

Focal adhesions are large multi-protein assemblies that form at the basal surface of cells on planar dishes, which mediate cell signaling, force transduction, and adhesion to the substratum. While much is known about focal adhesion components in 2-D systems, their role in migrating cells within a mo...

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Detalles Bibliográficos
Autores principales: Fraley, Stephanie I., Feng, Yunfeng, Krishnamurthy, Ranjini, Kim, Dong-Hwee, Celedon, Alfredo, Longmore, Gregory D., Wirtz, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116660/
https://www.ncbi.nlm.nih.gov/pubmed/20473295
http://dx.doi.org/10.1038/ncb2062