Increased Expression of the Dyslexia Candidate Gene DCDC2 Affects Length and Signaling of Primary Cilia in Neurons

DCDC2 is one of the candidate susceptibility genes for dyslexia. It belongs to the superfamily of doublecortin domain containing proteins that bind to microtubules, and it has been shown to be involved in neuronal migration. We show that the Dcdc2 protein localizes to the primary cilium in primary r...

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Detalles Bibliográficos
Autores principales: Massinen, Satu, Hokkanen, Marie-Estelle, Matsson, Hans, Tammimies, Kristiina, Tapia-Páez, Isabel, Dahlström-Heuser, Vanina, Kuja-Panula, Juha, Burghoorn, Jan, Jeppsson, Kristian E., Swoboda, Peter, Peyrard-Janvid, Myriam, Toftgård, Rune, Castrén, Eero, Kere, Juha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116825/
https://www.ncbi.nlm.nih.gov/pubmed/21698230
http://dx.doi.org/10.1371/journal.pone.0020580

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