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Cten Is Targeted by Kras Signalling to Regulate Cell Motility in the Colon and Pancreas

CTEN/TNS4 is an oncogene in colorectal cancer (CRC) which enhances cell motility although the mechanism of Cten regulation is unknown. We found an association between high Cten expression and KRAS/BRAF mutation in a series of CRC cell lines (p = 0.03) and hypothesised that Kras may regulate Cten. To...

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Detalles Bibliográficos
Autores principales: Al-Ghamdi, Saleh, Albasri, Abdulkader, Cachat, Julien, Ibrahem, Salih, Muhammad, Belal A., Jackson, Darryl, Nateri, Abdolrahman S., Kindle, Karin B., Ilyas, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116852/
https://www.ncbi.nlm.nih.gov/pubmed/21698197
http://dx.doi.org/10.1371/journal.pone.0020919