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Molecular Cloning of a New Immunomodulatory Protein from Anoectochilus formosanus which Induces B Cell IgM Secretion through a T-Independent Mechanism

An immunomodulatory protein (IPAF) was purified and cloned from Anoectochilus formosanus, an Orchidaceae herbal plant in Asia. The major targeting immune cells of IPAF and its modulating effects toward B lymphocytes were investigated. Rapid amplification of cDNA ends (RACE) was conducted to clone th...

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Detalles Bibliográficos
Autores principales: Kuan, Yen-Chou, Wu, Tsai-Jen, Kuo, Che-Yu, Hsu, Ju-Chun, Chang, Wen-Ying, Sheu, Fuu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116865/
https://www.ncbi.nlm.nih.gov/pubmed/21698210
http://dx.doi.org/10.1371/journal.pone.0021004