M402, a Novel Heparan Sulfate Mimetic, Targets Multiple Pathways Implicated in Tumor Progression and Metastasis

Heparan sulfate proteoglycans (HSPGs) play a key role in shaping the tumor microenvironment by presenting growth factors, cytokines, and other soluble factors that are critical for host cell recruitment and activation, as well as promoting tumor progression, metastasis, and survival. M402 is a ratio...

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Detalles Bibliográficos
Autores principales: Zhou, He, Roy, Sucharita, Cochran, Edward, Zouaoui, Radouane, Chu, Chia Lin, Duffner, Jay, Zhao, Ganlin, Smith, Sean, Galcheva-Gargova, Zoya, Karlgren, Juliane, Dussault, Nancy, Kwan, Rain Y. Q., Moy, Erick, Barnes, Marishka, Long, Alison, Honan, Chris, Qi, Yi Wei, Shriver, Zachary, Ganguly, Tanmoy, Schultes, Birgit, Venkataraman, Ganesh, Kishimoto, Takashi Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116871/
https://www.ncbi.nlm.nih.gov/pubmed/21698156
http://dx.doi.org/10.1371/journal.pone.0021106

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