Cargando…

Fat in the skin: Triacylglycerol metabolism in keratinocytes and its role in the development of neutral lipid storage disease

Keratinocyte differentiation is essential for skin development and the formation of the skin permeability barrier. This process involves an orchestrated remodeling of lipids. The cleavage of precursor lipids from lamellar bodies by β-glucocerebrosidase, sphingomyelinase, phospholipases and sterol su...

Descripción completa

Detalles Bibliográficos
Autores principales:	Radner, Franz PW, Grond, Susanne, Haemmerle, Guenter, Lass, Achim, Zechner, Rudolf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2011
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117006/ https://www.ncbi.nlm.nih.gov/pubmed/21695016 http://dx.doi.org/10.4161/derm.3.2.15472

Ejemplares similares

Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation
por: Grond, Susanne, et al.
Publicado: (2016)

ABHD5 stimulates PNPLA1-mediated ω-O-acylceramide biosynthesis essential for a functional skin permeability barrier
por: Kien, Benedikt, et al.
Publicado: (2018)

FAT SIGNALS - Lipases and Lipolysis in Lipid Metabolism and Signaling
por: Zechner, Rudolf, et al.
Publicado: (2012)

Cardiac oxidative stress in a mouse model of neutral lipid storage disease()
por: Schrammel, Astrid, et al.
Publicado: (2013)

Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase
por: Chandak, Prakash G., et al.
Publicado: (2010)

Recharging your fats: CHARMM36 parameters for neutral lipids triacylglycerol and diacylglycerol
por: Campomanes, Pablo, et al.
Publicado: (2021)

ABHD5—A Regulator of Lipid Metabolism Essential for Diverse Cellular Functions
por: Schratter, Margarita, et al.
Publicado: (2022)

Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores
por: Lass, Achim, et al.
Publicado: (2011)

Triacylglycerol Storage in Lipid Droplets in Procyclic Trypanosoma brucei
por: Allmann, Stefan, et al.
Publicado: (2014)

Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids
por: Jaeger, Doris, et al.
Publicado: (2015)

Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A
por: Nagy, Harald M., et al.
Publicado: (2014)

Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling
por: Hofer, Peter, et al.
Publicado: (2015)

Endothelial dysfunction in a mouse model of human neutral lipid storage disease
por: Schrammel, Astrid, et al.
Publicado: (2013)

Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells
por: Taschler, Ulrike, et al.
Publicado: (2015)

The Effects of Dietary Fat Content and Triacylglycerol Structures on the Vitamin A Storage in Mice
por: Chen, Guoxun, et al.
Publicado: (2022)

ω-O-Acylceramides but not ω-hydroxy ceramides are required for healthy lamellar phase architecture of skin barrier lipids
por: Opálka, Lukáš, et al.
Publicado: (2022)

The Role of Adipose Triglyceride Lipase and Cytosolic Lipolysis in Cardiac Function and Heart Failure
por: Kintscher, Ulrich, et al.
Publicado: (2020)

ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6
por: Eichmann, Thomas O., et al.
Publicado: (2015)

Carboxylesterase 2 proteins are efficient diglyceride and monoglyceride lipases possibly implicated in metabolic disease
por: Chalhoub, Gabriel, et al.
Publicado: (2021)

Role of the ubiquitin–proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice
por: Mussbacher, Marion, et al.
Publicado: (2014)

Triacylglycerols and Other Lipids Profiling of Hemp By-Products
por: Banskota, Arjun H., et al.
Publicado: (2022)

Intestinal Mucosal Triacylglycerol Accumulation Secondary to Decreased Lipid Secretion in Obese and High Fat Fed Mice
por: Douglass, John D., et al.
Publicado: (2012)

Triacylglycerol Accumulation Activates the Mitochondrial Apoptosis Pathway in Macrophages
por: Aflaki, Elma, et al.
Publicado: (2011)

Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover
por: Grumet, Lukas, et al.
Publicado: (2016)

Cooperative lipolytic control of neuronal triacylglycerol by spastic paraplegia-associated enzyme DDHD2 and ATGL
por: Hofer, Peter, et al.
Publicado: (2023)

Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae
por: Yu, Wei-Luen, et al.
Publicado: (2011)

Triacylglycerols sequester monotopic membrane proteins to lipid droplets
por: Caillon, Lucie, et al.
Publicado: (2020)

Perilipin family members preferentially sequester to either triacylglycerol-specific or cholesteryl-ester-specific intracellular lipid storage droplets
por: Hsieh, Kai, et al.
Publicado: (2012)

FAT FLUX: enzymes, regulators, and pathophysiology of intracellular lipolysis
por: Zechner, Rudolf
Publicado: (2015)

Retinyl esters form lipid droplets independently of triacylglycerol and seipin
por: Molenaar, Martijn R., et al.
Publicado: (2021)

Skeletal Muscle Triacylglycerol Hydrolysis Does Not Influence Metabolic Complications of Obesity
por: Sitnick, Mitch T., et al.
Publicado: (2013)

Muscle MRI in neutral lipid storage disease (NLSD)
por: Garibaldi, Matteo, et al.
Publicado: (2017)

Mycobacterium marinum Degrades Both Triacylglycerols and Phospholipids from Its Dictyostelium Host to Synthesise Its Own Triacylglycerols and Generate Lipid Inclusions
por: Barisch, Caroline, et al.
Publicado: (2017)

Neutral Lipid Storage Diseases as Cellular Model to Study Lipid Droplet Function
por: Missaglia, Sara, et al.
Publicado: (2019)

Altered Lipid Droplet Dynamics in Hepatocytes Lacking Triacylglycerol Hydrolase Expression
por: Wang, Huajin, et al.
Publicado: (2010)

The Proteome of Cholesteryl-Ester-Enriched Versus Triacylglycerol-Enriched Lipid Droplets
por: Khor, Victor K., et al.
Publicado: (2014)

Changes in Triacylglycerols Content and Quality Control Implications of Coix Seeds during Processing and Storage
por: Tang, Weiwei, et al.
Publicado: (2022)

Melting, Crystallization, and In Vitro Digestion Properties of Fats Containing Stearoyl-Rich Triacylglycerols
por: Shin, Kwang-Seup, et al.
Publicado: (2021)

Individual Keratinocyte Necroses in the Epidermis Are Apoptotic Keratinocytes in the Skin
por: Tachibana, Mitsuhiro, et al.
Publicado: (2023)

Advanced lipodystrophy reverses fatty liver in mice lacking adipocyte hormone-sensitive lipase
por: Pajed, Laura, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_vjqgqpgevr1dst4ufihi2s76br