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Reprogramming Transcription via Distinct Classes of Enhancers Functionally Defined by eRNA
Mammalian genomes are populated with thousands of transcriptional enhancers that orchestrate cell type-specific gene expression programs1-4, but how those enhancers are exploited to institute alternative, signal-dependent transcriptional responses remains poorly understood. Here we present evidence...
Autores principales: | Wang, Dong, Garcia-Bassets, Ivan, Benner, Chris, Li, Wenbo, Su, Xue, Zhou, Yiming, Qiu, Jinsong, Liu, Wen, Kaikkonen, Minna, Ohgi, Kenny H., Glass, Christopher K., Rosenfeld, Michael G., Fu, Xiang-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117022/ https://www.ncbi.nlm.nih.gov/pubmed/21572438 http://dx.doi.org/10.1038/nature10006 |
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