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Batf controls the global regulators of class switch recombination in both B and T cells

The transcription factor Batf controls T(H)17 differentiation by regulating the expression of both RORγt and RORγt target genes such as Il17. Here, we report the mechanism by which Batf controls in vivo class switch recombination (CSR). In T cells, Batf directly controls expression of the transcript...

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Detalles Bibliográficos
Autores principales: Ise, Wataru, Kohyama, Masako, Schraml, Barbara U., Zhang, Tingting, Schwer, Bjoern, Basu, Uttiya, Alt, Frederick W., Tang, Jun, Oltz, Eugene M., Murphy, Theresa L., Murphy, Kenneth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117275/
https://www.ncbi.nlm.nih.gov/pubmed/21572431
http://dx.doi.org/10.1038/ni.2037