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Systematic exploration of error sources in pyrosequencing flowgram data
Motivation: 454 pyrosequencing, by Roche Diagnostics, has emerged as an alternative to Sanger sequencing when it comes to read lengths, performance and cost, but shows higher per-base error rates. Although there are several tools available for noise removal, targeting different application fields, d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117331/ https://www.ncbi.nlm.nih.gov/pubmed/21685085 http://dx.doi.org/10.1093/bioinformatics/btr251 |