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Small sets of interacting proteins suggest functional linkage mechanisms via Bayesian analogical reasoning
Motivation: Proteins and protein complexes coordinate their activity to execute cellular functions. In a number of experimental settings, including synthetic genetic arrays, genetic perturbations and RNAi screens, scientists identify a small set of protein interactions of interest. A working hypothe...
Autores principales: | Airoldi, Edoardo M., Heller, Katherine A., Silva, Ricardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117334/ https://www.ncbi.nlm.nih.gov/pubmed/21685095 http://dx.doi.org/10.1093/bioinformatics/btr236 |
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