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Error correction of high-throughput sequencing datasets with non-uniform coverage

Motivation: The continuing improvements to high-throughput sequencing (HTS) platforms have begun to unfold a myriad of new applications. As a result, error correction of sequencing reads remains an important problem. Though several tools do an excellent job of correcting datasets where the reads are...

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Detalles Bibliográficos
Autores principales: Medvedev, Paul, Scott, Eric, Kakaradov, Boyko, Pevzner, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117386/
https://www.ncbi.nlm.nih.gov/pubmed/21685062
http://dx.doi.org/10.1093/bioinformatics/btr208