Mixed-model coexpression: calculating gene coexpression while accounting for expression heterogeneity

Motivation: The analysis of gene coexpression is at the core of many types of genetic analysis. The coexpression between two genes can be calculated by using a traditional Pearson's correlation coefficient. However, unobserved confounding effects may cause inflation of the Pearson's correl...

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Detalles Bibliográficos
Autores principales: Furlotte, Nicholas A., Kang, Hyun Min, Ye, Chun, Eskin, Eleazar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Ismb/Eccb 2011 Proceedings Papers Committee July 17 to July 19, 2011, Vienna, Austria
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117390/
https://www.ncbi.nlm.nih.gov/pubmed/21685083
http://dx.doi.org/10.1093/bioinformatics/btr221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117390/
https://www.ncbi.nlm.nih.gov/pubmed/21685083
http://dx.doi.org/10.1093/bioinformatics/btr221

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