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Mixed-model coexpression: calculating gene coexpression while accounting for expression heterogeneity
Motivation: The analysis of gene coexpression is at the core of many types of genetic analysis. The coexpression between two genes can be calculated by using a traditional Pearson's correlation coefficient. However, unobserved confounding effects may cause inflation of the Pearson's correl...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117390/ https://www.ncbi.nlm.nih.gov/pubmed/21685083 http://dx.doi.org/10.1093/bioinformatics/btr221 |