The Legacy of a Founding Father of Modern Cell Biology: George Emil Palade (1912-2008)

George Emil Palade’s scientific contributions significantly advanced the field of modern cell biology. He pioneered a multidisciplinary approach, combining cell fractionation, biochemistry, and electron microscopy, which led to the identification of the ribosome as the site of protein synthesis and...

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Detalles Bibliográficos
Autores principales: Zorca, Suzana M., Zorca, Cornelia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2011
Materias:
Focus: Yale School of Medicine Bicentennial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117404/
https://www.ncbi.nlm.nih.gov/pubmed/21698042
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author Zorca, Suzana M.
Zorca, Cornelia E.
author_facet Zorca, Suzana M.
Zorca, Cornelia E.
author_sort Zorca, Suzana M.
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description George Emil Palade’s scientific contributions significantly advanced the field of modern cell biology. He pioneered a multidisciplinary approach, combining cell fractionation, biochemistry, and electron microscopy, which led to the identification of the ribosome as the site of protein synthesis and elucidated the eukaryotic secretory pathway. For these accomplishments, Palade, along with Albert Claude and Christian de Duve, won the 1974 Nobel Prize in Physiology or Medicine. This article provides an overview of Palade’s seminal research in the context of the early developments in the field.
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spelling pubmed-31174042011-06-22 The Legacy of a Founding Father of Modern Cell Biology: George Emil Palade (1912-2008) Zorca, Suzana M. Zorca, Cornelia E. Yale J Biol Med Focus: Yale School of Medicine Bicentennial George Emil Palade’s scientific contributions significantly advanced the field of modern cell biology. He pioneered a multidisciplinary approach, combining cell fractionation, biochemistry, and electron microscopy, which led to the identification of the ribosome as the site of protein synthesis and elucidated the eukaryotic secretory pathway. For these accomplishments, Palade, along with Albert Claude and Christian de Duve, won the 1974 Nobel Prize in Physiology or Medicine. This article provides an overview of Palade’s seminal research in the context of the early developments in the field. YJBM 2011-06 2011-06 /pmc/articles/PMC3117404/ /pubmed/21698042 Text en Copyright ©2011, Yale Journal of Biology and Medicine https://creativecommons.org/licenses/by-nc/3.0/This is an open access article distributed under the terms of the Creative Commons CC BY-NC license, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use the material for commercial purposes.
spellingShingle Focus: Yale School of Medicine Bicentennial
Zorca, Suzana M.
Zorca, Cornelia E.
The Legacy of a Founding Father of Modern Cell Biology: George Emil Palade (1912-2008)
title The Legacy of a Founding Father of Modern Cell Biology: George Emil Palade (1912-2008)
title_full The Legacy of a Founding Father of Modern Cell Biology: George Emil Palade (1912-2008)
title_fullStr The Legacy of a Founding Father of Modern Cell Biology: George Emil Palade (1912-2008)
title_full_unstemmed The Legacy of a Founding Father of Modern Cell Biology: George Emil Palade (1912-2008)
title_short The Legacy of a Founding Father of Modern Cell Biology: George Emil Palade (1912-2008)
title_sort legacy of a founding father of modern cell biology: george emil palade (1912-2008)
topic Focus: Yale School of Medicine Bicentennial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117404/
https://www.ncbi.nlm.nih.gov/pubmed/21698042
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