Cargando…

Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in

The tumor suppressor LKB1 has emerged as a critical regulator of cell polarity and energy-metabolism. Studies in diverse model organisms continue to unravel the pathways downstream of LKB1; the emerging picture is that the outcomes of LKB1 signaling are mediated by a plethora of tissue-specific and...

Descripción completa

Detalles Bibliográficos
Autores principales: van der Velden, Yme U., Haramis, Anna-Pavlina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117450/
https://www.ncbi.nlm.nih.gov/pubmed/21721170
_version_ 1782206335483379712
author van der Velden, Yme U.
Haramis, Anna-Pavlina G.
author_facet van der Velden, Yme U.
Haramis, Anna-Pavlina G.
author_sort van der Velden, Yme U.
collection PubMed
description The tumor suppressor LKB1 has emerged as a critical regulator of cell polarity and energy-metabolism. Studies in diverse model organisms continue to unravel the pathways downstream of LKB1; the emerging picture is that the outcomes of LKB1 signaling are mediated by a plethora of tissue-specific and context-dependent effectors.
format Online
Article
Text
id pubmed-3117450
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Impact Journals LLC
record_format MEDLINE/PubMed
spelling pubmed-31174502011-06-20 Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in van der Velden, Yme U. Haramis, Anna-Pavlina G. Aging (Albany NY) Review The tumor suppressor LKB1 has emerged as a critical regulator of cell polarity and energy-metabolism. Studies in diverse model organisms continue to unravel the pathways downstream of LKB1; the emerging picture is that the outcomes of LKB1 signaling are mediated by a plethora of tissue-specific and context-dependent effectors. Impact Journals LLC 2011-04-26 /pmc/articles/PMC3117450/ /pubmed/21721170 Text en Copyright: © 2011 van der Velden and Haramis http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
spellingShingle Review
van der Velden, Yme U.
Haramis, Anna-Pavlina G.
Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in
title Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in
title_full Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in
title_fullStr Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in
title_full_unstemmed Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in
title_short Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in
title_sort insights from model organisms on the functions of the tumor suppressor protein lkb1: zebrafish chips in
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117450/
https://www.ncbi.nlm.nih.gov/pubmed/21721170
work_keys_str_mv AT vanderveldenymeu insightsfrommodelorganismsonthefunctionsofthetumorsuppressorproteinlkb1zebrafishchipsin
AT haramisannapavlinag insightsfrommodelorganismsonthefunctionsofthetumorsuppressorproteinlkb1zebrafishchipsin