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Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in
The tumor suppressor LKB1 has emerged as a critical regulator of cell polarity and energy-metabolism. Studies in diverse model organisms continue to unravel the pathways downstream of LKB1; the emerging picture is that the outcomes of LKB1 signaling are mediated by a plethora of tissue-specific and...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117450/ https://www.ncbi.nlm.nih.gov/pubmed/21721170 |
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author | van der Velden, Yme U. Haramis, Anna-Pavlina G. |
author_facet | van der Velden, Yme U. Haramis, Anna-Pavlina G. |
author_sort | van der Velden, Yme U. |
collection | PubMed |
description | The tumor suppressor LKB1 has emerged as a critical regulator of cell polarity and energy-metabolism. Studies in diverse model organisms continue to unravel the pathways downstream of LKB1; the emerging picture is that the outcomes of LKB1 signaling are mediated by a plethora of tissue-specific and context-dependent effectors. |
format | Online Article Text |
id | pubmed-3117450 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Impact Journals LLC |
record_format | MEDLINE/PubMed |
spelling | pubmed-31174502011-06-20 Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in van der Velden, Yme U. Haramis, Anna-Pavlina G. Aging (Albany NY) Review The tumor suppressor LKB1 has emerged as a critical regulator of cell polarity and energy-metabolism. Studies in diverse model organisms continue to unravel the pathways downstream of LKB1; the emerging picture is that the outcomes of LKB1 signaling are mediated by a plethora of tissue-specific and context-dependent effectors. Impact Journals LLC 2011-04-26 /pmc/articles/PMC3117450/ /pubmed/21721170 Text en Copyright: © 2011 van der Velden and Haramis http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited |
spellingShingle | Review van der Velden, Yme U. Haramis, Anna-Pavlina G. Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in |
title | Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in |
title_full | Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in |
title_fullStr | Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in |
title_full_unstemmed | Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in |
title_short | Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in |
title_sort | insights from model organisms on the functions of the tumor suppressor protein lkb1: zebrafish chips in |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117450/ https://www.ncbi.nlm.nih.gov/pubmed/21721170 |
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