Cargando…

Accelerated in vivo epidermal telomere loss in Werner syndrome

Many data pertaining to the accelerated telomere loss in cultured cells derived from Werner syndrome (WS), a representative premature aging syndrome, have been accumulated. However, there have been no definitive data on in vivo telomere shortening in WS patients. In the present study, we measured te...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ishikawa, Naoshi, Nakamura, Ken-Ichi, Izumiyama-Shimomura, Naotaka, Aida, Junko, Ishii, Akio, Goto, Makoto, Ishikawa, Yuichi, Asaka, Reimi, Matsuura, Masaaki, Hatamochi, Atsushi, Kuroiwa, Mie, Takubo, Kaiyo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2011
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117457/ https://www.ncbi.nlm.nih.gov/pubmed/21732564

Ejemplares similares

Association of telomere shortening in myocardium with heart weight gain and cause of death
por: Terai, Masanori, et al.
Publicado: (2013)

Telomere attrition and restoration in the normal teleost Oryzias latipes are linked to growth rate and telomerase activity at each life stage
por: Hatakeyama, Hitoshi, et al.
Publicado: (2016)

Telomere length dynamics in the human pituitary gland: robust preservation throughout adult life to centenarian age
por: Ishikawa, Naoshi, et al.
Publicado: (2011)

Telomere Shortening in the Esophagus of Japanese Alcoholics: Relationships with Chromoendoscopic Findings, ALDH2 and ADH1B Genotypes and Smoking History
por: Aida, Junko, et al.
Publicado: (2013)

Q-FISH Measurement of Hepatocyte Telomere Lengths in Donor Liver and Graft after Pediatric Living-Donor Liver Transplantation: Donor Age Affects Telomere Length Sustainability
por: Kawano, Youichi, et al.
Publicado: (2014)

Gradual Telomere Shortening and Increasing Chromosomal Instability among PanIN Grades and Normal Ductal Epithelia with and without Cancer in the Pancreas
por: Matsuda, Yoko, et al.
Publicado: (2015)

Stemness and anti‐cancer drug resistance in ATP‐binding cassette subfamily G member 2 highly expressed pancreatic cancer is induced in 3D culture conditions
por: Sasaki, Norihiko, et al.
Publicado: (2018)

ATF7 mediates TNF-α–induced telomere shortening
por: Maekawa, Toshio, et al.
Publicado: (2018)

Atypical Osteosarcomas in Werner Syndrome (Adult Progeria)
por: Ishikawa, Yuichi, et al.
Publicado: (2000)

The ceramide [NP]/[NS] ratio in the stratum corneum is a potential marker for skin properties and epidermal differentiation
por: Yokose, Urara, et al.
Publicado: (2020)

Accelerated telomere shortening in adrenal zona reticularis in patients with prolonged critical illness
por: Nonaka, Keisuke, et al.
Publicado: (2023)

Regression of Metastatic Liver Tumors in Rats Treated with Angiogenesis Inhibitor TNP‐470: Occurrence of Apoptosis and Necrosis
por: Ahmed, Motahar H., et al.
Publicado: (1997)

Werner Syndrome
por: Chen, Lishan, et al.
Publicado: (2002)

Telomeric protein TRF2 protects Holliday junctions with telomeric arms from displacement by the Werner syndrome helicase
por: Nora, Gerald J., et al.
Publicado: (2010)

Modulation of Telomeres in Alternative Lengthening of Telomeres Type I Like Human Cells by the Expression of Werner Protein and Telomerase
por: Siddiqa, Aisha, et al.
Publicado: (2012)

Successful Cord Blood Transplantation in a Werner Syndrome Patient with High-risk Myelodysplastic Syndrome
por: Hayashi, Kiyohito, et al.
Publicado: (2018)

Mechanism and substrate specificity of telomeric protein POT1 stimulation of the Werner syndrome helicase
por: Sowd, Gregory, et al.
Publicado: (2008)

Sequence-specific processing of telomeric 3' overhangs by the Werner syndrome protein exonuclease activity
por: Li, Baomin, et al.
Publicado: (2009)

Werner Syndrome-specific induced pluripotent stem cells: recovery of telomere function by reprogramming
por: Shimamoto, Akira, et al.
Publicado: (2015)

H19 long non-coding RNA contributes to sphere formation and invasion through regulation of CD24 and integrin expression in pancreatic cancer cells
por: Sasaki, Norihiko, et al.
Publicado: (2018)

Columnar Metaplasia in Three Types of Surgical Mouse Models of Esophageal Reflux
por: Terabe, Fabio, et al.
Publicado: (2017)

Accelerated epigenetic aging in Werner syndrome
por: Maierhofer, Anna, et al.
Publicado: (2017)

Sitagliptin Successfully Ameliorates Glycemic Control in Werner Syndrome With Diabetes
por: Kitamoto, Takumi, et al.
Publicado: (2012)

Werner syndrome: a model for sarcopenia due to accelerated aging
por: Yamaga, Masaya, et al.
Publicado: (2017)

The Werner Syndrome Protein Suppresses Telomeric Instability Caused by Chromium (VI) Induced DNA Replication Stress
por: Liu, Fu-Jun, et al.
Publicado: (2010)

Strand exchange of telomeric DNA catalyzed by the Werner syndrome protein (WRN) is specifically stimulated by TRF2
por: Edwards, Deanna N., et al.
Publicado: (2014)

Portrait of replication stress viewed from telomeres
por: Ishikawa, Fuyuki
Publicado: (2013)

Sitagliptin Improves Postprandial Hyperglycemia by Inhibiting Glucagon Secretion in Werner Syndrome With Diabetes
por: Watanabe, Kaneyuki, et al.
Publicado: (2013)

The Gustaf Werner Institute
Publicado: (1982)

Werner Von Siemens
por: Jiménez Alarcón, Moisés
Publicado: (1989)

Oxidative stress and antioxidant response in fibroblasts from Werner and Atypical Werner Syndromes
por: Seco-Cervera, Marta, et al.
Publicado: (2014)

Werner syndrome through the lens of tissue and tumour genomics
por: Tokita, Mari, et al.
Publicado: (2016)

A Case Report of Werner’s Syndrome With a Novel Mutation From India
por: Singh, Ajeet, et al.
Publicado: (2020)

Acrolein-Exposed Normal Human Lung Fibroblasts in Vitro: Cellular Senescence, Enhanced Telomere Erosion, and Degradation of Werner’s Syndrome Protein
por: Jang, Jun-Ho, et al.
Publicado: (2014)

Werner Kienzle (1936 – 2016)
Publicado: (2016)

L'Institut Gustaf Werner
Publicado: (1982)

Werner's Syndrome (Progeria in the Adult)
por: Grant, Alan P.
Publicado: (1957)

Werner Heisenberg - Life and Work
Publicado: (2002)

Werner Heisenberg - Life and Work
Publicado: (2002)

Werner Heisenberg memorial lecture
por: CERN Press Office. Geneva
Publicado: (1976)

Cannot write session to /tmp/vufind_sessions/sess_1f23p1labpdv6tuelve7m5j0ul