Cargando…

Minocycline fails to modulate cerebrospinal fluid HIV infection or immune activation in chronic untreated HIV-1 infection: results of a pilot study

BACKGROUND: Minocycline is a tetracycline antibiotic that has been shown to attenuate central nervous system (CNS) lentivirus infection, immune activation, and brain injury in model systems. To initiate assessment of minocycline as an adjuvant therapy in human CNS HIV infection, we conducted an open...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ho, Emily L, Spudich, Serena S, Lee, Evelyn, Fuchs, Dietmar, Sinclair, Elizabeth, Price, Richard W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117676/ https://www.ncbi.nlm.nih.gov/pubmed/21569420 http://dx.doi.org/10.1186/1742-6405-8-17

Ejemplares similares

Cellular Composition of Cerebrospinal Fluid in HIV-1 Infected and Uninfected Subjects
por: Ho, Emily L., et al.
Publicado: (2013)

Raltegravir Cerebrospinal Fluid Concentrations in HIV-1 Infection
por: Yilmaz, Aylin, et al.
Publicado: (2009)

Progressive increase in central nervous system immune activation in untreated primary HIV-1 infection
por: Suh, Joome, et al.
Publicado: (2014)

Compartmentalization of cerebrospinal fluid inflammation across the spectrum of untreated HIV-1 infection, central nervous system injury and viral suppression
por: Gisslen, Magnus, et al.
Publicado: (2021)

The cerebrospinal fluid proteome in HIV infection: change associated with disease severity
por: Angel, Thomas E, et al.
Publicado: (2012)

Approach to Cerebrospinal Fluid (CSF) Biomarker Discovery and Evaluation in HIV Infection
por: Price, Richard W., et al.
Publicado: (2013)

Cerebrospinal Fluid (CSF) Neuronal Biomarkers across the Spectrum of HIV Infection: Hierarchy of Injury and Detection
por: Peterson, Julia, et al.
Publicado: (2014)

Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection
por: Hagberg, Lars, et al.
Publicado: (2010)

Cerebrospinal Fluid Concentrations of the Synaptic Marker Neurogranin in Neuro-HIV and Other Neurological Disorders
por: Yilmaz, Aylin, et al.
Publicado: (2019)

Amyloid and tau cerebrospinal fluid biomarkers in HIV infection
por: Gisslén, Magnus, et al.
Publicado: (2009)

Cerebrospinal fluid HIV infection and pleocytosis: Relation to systemic infection and antiretroviral treatment
por: Spudich, Serena S, et al.
Publicado: (2005)

Deep sequencing of HIV-1 variants from paired plasma and cerebrospinal fluid during primary HIV infection
por: Gega, Arjet, et al.
Publicado: (2015)

Cerebrospinal Fluid Viral Load Across the Spectrum of Untreated Human Immunodeficiency Virus Type 1 (HIV-1) Infection: A Cross-Sectional Multicenter Study
por: Ulfhammer, Gustaf, et al.
Publicado: (2021)

Soluble CD14 in cerebrospinal fluid is associated with markers of inflammation and axonal damage in untreated HIV-infected patients: a retrospective cross-sectional study
por: Jespersen, Sofie, et al.
Publicado: (2016)

Cerebrospinal fluid viral breakthrough in two HIV-infected subjects on darunavir/ritonavir monotherapy
por: Gisslén, Magnus, et al.
Publicado: (2012)

Cerebrospinal fluid neopterin decay characteristics after initiation of antiretroviral therapy
por: Yilmaz, Aylin, et al.
Publicado: (2013)

Cerebrospinal fluid CD4+ T cell infection in humans and macaques during acute HIV-1 and SHIV infection
por: Sharma, Vishakha, et al.
Publicado: (2021)

Cerebrospinal Fluid Viral Load and Intrathecal Immune Activation in Individuals Infected with Different HIV-1 Genetic Subtypes
por: Abdulle, Sahra, et al.
Publicado: (2008)

Cerebrospinal fluid levels of glial marker YKL-40 strongly associated with axonal injury in HIV infection
por: Hermansson, Linn, et al.
Publicado: (2019)

CSF concentrations of soluble TREM2 as a marker of microglial activation in HIV-1 infection
por: Gisslén, Magnus, et al.
Publicado: (2018)

Plasma Concentration of the Neurofilament Light Protein (NFL) is a Biomarker of CNS Injury in HIV Infection: A Cross-Sectional Study
por: Gisslén, Magnus, et al.
Publicado: (2015)

Cerebrospinal fluid signs of neuronal damage after antiretroviral treatment interruption in HIV-1 infection
por: Gisslén, Magnus, et al.
Publicado: (2005)

Elevated Cerebrospinal Fluid Anti-CD4 Autoantibody Levels in HIV Associate with Neuroinflammation
por: Cheng, Da, et al.
Publicado: (2022)

Cerebrospinal fluid CXCL13 in Lyme neuroborreliosis and asymptomatic HIV infection
por: Bremell, Daniel, et al.
Publicado: (2013)

The cerebrospinal fluid biomarker profile in an HIV-infected subject with Alzheimer’s disease
por: Mäkitalo, Signar, et al.
Publicado: (2015)

HBV infection in untreated HIV-infected adults in Maputo, Mozambique
por: Chambal, Lúcia Mabalane, et al.
Publicado: (2017)

Distribution of Human Immunodeficiency Virus (HIV) Ribonucleic Acid in Cerebrospinal Fluid and Blood Is Linked to CD4/CD8 Ratio During Acute HIV
por: Chan, Phillip, et al.
Publicado: (2018)

Chemokines in cerebrospinal fluid correlate with cerebral metabolite patterns in HIV-infected individuals
por: Letendre, Scott L., et al.
Publicado: (2011)

Normalisation of cerebrospinal fluid biomarkers parallels improvement of neurological symptoms following HAART in HIV dementia – case report
por: Andersson, Lars-Magnus, et al.
Publicado: (2006)

Corrigendum to: “Plasma concentration of the neurofilament light protein (NFL) is a biomarker of CNS injury in HIV infection: A cross-sectional study” [EBioMedicine 3 (216) 135–140]
por: Gisslén, Magnus, et al.
Publicado: (2016)

Correction: HBV infection in untreated HIV-infected adults in Maputo, Mozambique
por: Chambal, Lúcia Mabalane, et al.
Publicado: (2017)

HIV and Neurocognitive Dysfunction
por: Spudich, Serena
Publicado: (2013)

European Mitochondrial DNA Haplogroups are Associated with Cerebrospinal Fluid Biomarkers of Inflammation in HIV Infection
por: Samuels, David C., et al.
Publicado: (2016)

B Cell Compartmentalization in Blood and Cerebrospinal Fluid of HIV-Infected Ugandans with Cryptococcal Meningitis
por: Okurut, Samuel, et al.
Publicado: (2020)

A case report of untreatable HIV infection in Harare, Zimbabwe
por: Chimbetete, Cleophas, et al.
Publicado: (2019)

Untreated Giant Macroprolactinoma with Chronic Cerebrospinal Fluid Leakage: An Unusual Complication
por: Mad Naser, Mohamad Nazrulhisham, et al.
Publicado: (2019)

Cerebrospinal fluid soluble CD30 elevation despite suppressive antiretroviral therapy in individuals living with HIV-1
por: Peluso, Michael J, et al.
Publicado: (2020)

Postnatal Cytomegalovirus Exposure in Infants of Antiretroviral-Treated and Untreated HIV-Infected Mothers
por: Meyer, Sarah A., et al.
Publicado: (2014)

HIV-1 is Transported into the Central Nervous System by Trafficking Infected Cells
por: Kincer, Laura P., et al.
Publicado: (2023)

Dolutegravir Cerebrospinal Fluid Diffusion in HIV-1–Infected Patients with Central Nervous System Impairment
por: Gelé, Thibaut, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_l3ge04btaridf7phb4jpt9df2e