The Regulation of Leptin, Leptin Receptor and Pro-opiomelanocortin Expression by N-3 PUFAs in Diet-Induced Obese Mice Is Not Related to the Methylation of Their Promoters

BACKGROUND: The expression of leptin is increased in obesity and inhibited by n-3 polyunsaturated fatty acids (n-3 PUFAs), but the underlying molecular mechanisms have not been firmly established. METHODS: In this study, we investigated the effects of dietary n-3 PUFAs on the methylation of CpG isla...

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Detalles Bibliográficos
Autores principales: Fan, Chaonan, Liu, Xinli, Shen, Wenwen, Deckelbaum, Richard J, Qi, Kemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117679/
https://www.ncbi.nlm.nih.gov/pubmed/21609458
http://dx.doi.org/10.1186/1743-7075-8-31

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