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Low doses of 3-aminobenzamide, a poly(ADP-ribose) polymerase inhibitor, stimulate angiogenesis by regulating expression of urokinase type plasminogen activator and matrix metalloprotease 2

BACKGROUND: Poly(ADP-Ribose) polymerase (PARP) activity has been demonstrated fundamental in many cellular processes, including DNA repair, cell proliferation and differentiation. In particular, PARP activity has been recently found to affect proliferation, migration, and tube formation of human umb...

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Detalles Bibliográficos
Autores principales: Caldini, Riccardo, Fanti, Elena, Magnelli, Lucia, Barletta, Emanuela, Tanganelli, Elisabetta, Zampieri, Michele, Chevanne, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117742/
https://www.ncbi.nlm.nih.gov/pubmed/21595892
http://dx.doi.org/10.1186/2045-824X-3-12