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Reduced CSF turnover and decreased ventricular Aβ42 levels are related
BACKGROUND: The appearance of Aβ42 peptide deposits is admitted to be a key event in the pathogenesis of Alzheimer's disease, although amyloid deposits also occur in aged non-demented subjects. Aβ42 is a degradation product of the amyloid protein precursor (APP). It can be catabolized by severa...
Autores principales: | Serot, Jean-Marie, Peltier, Johann, Fichten, Antony, Ledeme, Nelly, Bourgeois, Anne-Marie, Jouanny, Pierre, Toussaint, Patrick, Legars, Daniel, Godefroy, Olivier, Mazière, Jean-Claude |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117747/ https://www.ncbi.nlm.nih.gov/pubmed/21569454 http://dx.doi.org/10.1186/1471-2202-12-42 |
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