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System Integration - A Major Step toward Lab on a Chip
Microfluidics holds great promise to revolutionize various areas of biological engineering, such as single cell analysis, environmental monitoring, regenerative medicine, and point-of-care diagnostics. Despite the fact that intensive efforts have been devoted into the field in the past decades, micr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117764/ https://www.ncbi.nlm.nih.gov/pubmed/21612614 http://dx.doi.org/10.1186/1754-1611-5-6 |
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author | Sin, Mandy LY Gao, Jian Liao, Joseph C Wong, Pak Kin |
author_facet | Sin, Mandy LY Gao, Jian Liao, Joseph C Wong, Pak Kin |
author_sort | Sin, Mandy LY |
collection | PubMed |
description | Microfluidics holds great promise to revolutionize various areas of biological engineering, such as single cell analysis, environmental monitoring, regenerative medicine, and point-of-care diagnostics. Despite the fact that intensive efforts have been devoted into the field in the past decades, microfluidics has not yet been adopted widely. It is increasingly realized that an effective system integration strategy that is low cost and broadly applicable to various biological engineering situations is required to fully realize the potential of microfluidics. In this article, we review several promising system integration approaches for microfluidics and discuss their advantages, limitations, and applications. Future advancements of these microfluidic strategies will lead toward translational lab-on-a-chip systems for a wide spectrum of biological engineering applications. |
format | Online Article Text |
id | pubmed-3117764 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-31177642011-06-18 System Integration - A Major Step toward Lab on a Chip Sin, Mandy LY Gao, Jian Liao, Joseph C Wong, Pak Kin J Biol Eng Review Microfluidics holds great promise to revolutionize various areas of biological engineering, such as single cell analysis, environmental monitoring, regenerative medicine, and point-of-care diagnostics. Despite the fact that intensive efforts have been devoted into the field in the past decades, microfluidics has not yet been adopted widely. It is increasingly realized that an effective system integration strategy that is low cost and broadly applicable to various biological engineering situations is required to fully realize the potential of microfluidics. In this article, we review several promising system integration approaches for microfluidics and discuss their advantages, limitations, and applications. Future advancements of these microfluidic strategies will lead toward translational lab-on-a-chip systems for a wide spectrum of biological engineering applications. BioMed Central 2011-05-25 /pmc/articles/PMC3117764/ /pubmed/21612614 http://dx.doi.org/10.1186/1754-1611-5-6 Text en Copyright ©2011 Sin et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Sin, Mandy LY Gao, Jian Liao, Joseph C Wong, Pak Kin System Integration - A Major Step toward Lab on a Chip |
title | System Integration - A Major Step toward Lab on a Chip |
title_full | System Integration - A Major Step toward Lab on a Chip |
title_fullStr | System Integration - A Major Step toward Lab on a Chip |
title_full_unstemmed | System Integration - A Major Step toward Lab on a Chip |
title_short | System Integration - A Major Step toward Lab on a Chip |
title_sort | system integration - a major step toward lab on a chip |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117764/ https://www.ncbi.nlm.nih.gov/pubmed/21612614 http://dx.doi.org/10.1186/1754-1611-5-6 |
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