The IFN-γ-Inducible GTPase, Irga6, Protects Mice against Toxoplasma gondii but Not against Plasmodium berghei and Some Other Intracellular Pathogens

Clearance of infection with intracellular pathogens in mice involves interferon-regulated GTPases of the IRG protein family. Experiments with mice genetically deficient in members of this family such as Irgm1(LRG-47), Irgm3(IGTP), and Irgd(IRG-47) has revealed a critical role in microbial clearance,...

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Detalles Bibliográficos
Autores principales: Liesenfeld, Oliver, Parvanova, Iana, Zerrahn, Jens, Han, Seong-Ji, Heinrich, Frederik, Muñoz, Melba, Kaiser, Frank, Aebischer, Toni, Buch, Thorsten, Waisman, Ari, Reichmann, Gaby, Utermöhlen, Olaf, von Stebut, Esther, von Loewenich, Friederike D., Bogdan, Christian, Specht, Sabine, Saeftel, Michael, Hoerauf, Achim, Mota, Maria M., Könen-Waisman, Stephanie, Kaufmann, Stefan H. E., Howard, Jonathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117789/
https://www.ncbi.nlm.nih.gov/pubmed/21698150
http://dx.doi.org/10.1371/journal.pone.0020568

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