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Variation in Human Recombination Rates and Its Genetic Determinants

BACKGROUND: Despite the fundamental role of crossing-over in the pairing and segregation of chromosomes during human meiosis, the rates and placements of events vary markedly among individuals. Characterizing this variation and identifying its determinants are essential steps in our understanding of...

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Detalles Bibliográficos
Autores principales: Fledel-Alon, Adi, Leffler, Ellen Miranda, Guan, Yongtao, Stephens, Matthew, Coop, Graham, Przeworski, Molly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117798/
https://www.ncbi.nlm.nih.gov/pubmed/21698098
http://dx.doi.org/10.1371/journal.pone.0020321

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