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Anchored Design of Protein-Protein Interfaces
BACKGROUND: Few existing protein-protein interface design methods allow for extensive backbone rearrangements during the design process. There is also a dichotomy between redesign methods, which take advantage of the native interface, and de novo methods, which produce novel binders. METHODOLOGY: He...
Autores principales: | Lewis, Steven M., Kuhlman, Brian A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117852/ https://www.ncbi.nlm.nih.gov/pubmed/21698112 http://dx.doi.org/10.1371/journal.pone.0020872 |
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