Cargando…

Substrate Specifity Profiling of the Aspergillus fumigatus Proteolytic Secretome Reveals Consensus Motifs with Predominance of Ile/Leu and Phe/Tyr

BACKGROUND: The filamentous fungus Aspergillus fumigatus (AF) can cause devastating infections in immunocompromised individuals. Early diagnosis improves patient outcomes but remains challenging because of the limitations of current methods. To augment the clinician's toolkit for rapid diagnosi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Watson, Douglas S., Feng, Xizhi, Askew, David S., Jambunathan, Kalyani, Kodukula, Krishna, Galande, Amit K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117871/ https://www.ncbi.nlm.nih.gov/pubmed/21695046 http://dx.doi.org/10.1371/journal.pone.0021001

Ejemplares similares

Impact of the Lectin Chaperone Calnexin on the Stress Response, Virulence and Proteolytic Secretome of the Fungal Pathogen Aspergillus fumigatus
por: Powers-Fletcher, Margaret V., et al.
Publicado: (2011)

Tyr78Phe Transthyretin Mutation with Predominant Motor Neuropathy as the Initial Presentation
por: Riboldi, Giulietta, et al.
Publicado: (2011)

Transcriptome and secretome analysis of Aspergillus fumigatus in the presence of sugarcane bagasse
por: de Gouvêa, Paula Fagundes, et al.
Publicado: (2018)

Comparative systems analysis of the secretome of the opportunistic pathogen Aspergillus fumigatus and other Aspergillus species
por: Vivek-Ananth, R. P., et al.
Publicado: (2018)

The Dipeptides Ile-Tyr and Ser-Tyr Exert Distinct Effects on Catecholamine Metabolism in the Mouse Brainstem
por: Moriyasu, Kazuki, et al.
Publicado: (2016)

Data for iTRAQ secretomic analysis of Aspergillus fumigatus in response to different carbon sources
por: Adav, Sunil S., et al.
Publicado: (2015)

Exposure to the Pseudomonas aeruginosa secretome alters the proteome and secondary metabolite production of Aspergillus fumigatus
por: Margalit, Anatte, et al.
Publicado: (2022)

Deletion of the sec4 Homolog srgA from Aspergillus fumigatus Is Associated with an Impaired Stress Response, Attenuated Virulence and Phenotypic Heterogeneity
por: Powers-Fletcher, Margaret V., et al.
Publicado: (2013)

Development of a genotyping tool for a functionally relevant CYP2C19 allele (Phe100Asn, Ala103Val and Ile112Leu) in cynomolgus macaques
por: UNO, Yasuhiro, et al.
Publicado: (2015)

Evaluation of the Complex p.[Leu467Phe;Phe508del] CFTR Allele in the Intestinal Organoids Model: Implications for Therapy
por: Kondratyeva, Elena, et al.
Publicado: (2022)

Secretome diversity and quantitative analysis of cellulolytic Aspergillus fumigatus Z5 in the presence of different carbon sources
por: Liu, Dongyang, et al.
Publicado: (2013)

The Aspergillus fumigatus Secretome Alters the Proteome of Pseudomonas aeruginosa to Stimulate Bacterial Growth: Implications for Co-infection
por: Margalit, Anatte, et al.
Publicado: (2020)

Comparisons of Interfacial Phe, Tyr, and Trp Residues as Determinants of Orientation and Dynamics for GWALP Transmembrane Peptides
por: Sparks, Kelsey A., et al.
Publicado: (2014)

The Phe-Phe Motif for Peptide Self-Assembly in Nanomedicine
por: Marchesan, Silvia, et al.
Publicado: (2015)

Aspergillus fumigatus in Poultry
por: Arné, Pascal, et al.
Publicado: (2011)

Characterization of POLE c.1373A > T p.(Tyr458Phe), causing high cancer risk
por: Rocque, Mariève J., et al.
Publicado: (2023)

PTPN11 c.853T>C (p.Phe285Leu) mutation in Noonan syndrome with chylothorax
por: Watanabe, Daisuke, et al.
Publicado: (2022)

The Zn(2)Cys(6)-type transcription factor LeuB cross-links regulation of leucine biosynthesis and iron acquisition in Aspergillus fumigatus
por: Long, Nanbiao, et al.
Publicado: (2018)

Structural Basis for Differences in Dynamics Induced by Leu Versus Ile Residues in the CD Loop of Kir Channels
por: Lü, Shouqin, et al.
Publicado: (2015)

Regulation of Development in Aspergillus nidulans and Aspergillus fumigatus
por: Yu, Jae-Hyuk
Publicado: (2010)

The Conserved Tyr176/Leu177 Motif in the α-Helix 9 of the Feline Immunodeficiency Virus Capsid Protein Is Critical for Gag Particle Assembly
por: Ovejero, César A., et al.
Publicado: (2019)

Doxycycline-regulated gene expression in the opportunistic fungal pathogen Aspergillus fumigatus
por: Vogt, Keith, et al.
Publicado: (2005)

Antioxidant Activity of Aspergillus fumigatus
por: Arora, Daljit Singh, et al.
Publicado: (2011)

Role of Hydrophobins in Aspergillus fumigatus
por: Valsecchi, Isabel, et al.
Publicado: (2017)

SENSITIZATION TO ASPERGILLUS FUMIGATUS IN FIBROCYSTICS
por: Rosario, Nelson A., et al.
Publicado: (2018)

Culturing and Mating of Aspergillus fumigatus
por: Ashton, George D., et al.
Publicado: (2019)

Phe362Tyr in AChE: A Major Factor Responsible for Azamethiphos Resistance in Lepeophtheirus salmonis in Norway
por: Kaur, Kiranpreet, et al.
Publicado: (2016)

2′,6′-Dimethylphenylalanine: A Useful Aromatic Amino Acid Surrogate for Tyr or Phe Residue in Opioid Peptides
por: Sasaki, Yusuke, et al.
Publicado: (2012)

Synthesis, Antiproliferative Effect and In Silico LogP Prediction of BIM-23052 Analogs Containing Tyr Instead of Phe
por: Danalev, Dancho, et al.
Publicado: (2023)

High Concentration of Protein Oxidation Biomarker O-Tyr/Phe Predicts Better Outcome in Childhood Bacterial Meningitis
por: Rugemalira, Emilie, et al.
Publicado: (2023)

Rapid Host Defense against Aspergillus fumigatus Involves Alveolar Macrophages with a Predominance of Alternatively Activated Phenotype
por: Bhatia, Shikha, et al.
Publicado: (2011)

MGMT Leu84Phe Polymorphism Contributes to Cancer Susceptibility: Evidence from 44 Case-Control Studies
por: Liu, Jun, et al.
Publicado: (2013)

Hb Heathrow [β103(G5)Phe→Leu], a First Report in an Asian Patient with Erythrocytosis
por: Shin, Sang-Yong, et al.
Publicado: (2017)

Multi-Factor Regulation of the Master Modulator LeuO for the Cyclic-(Phe-Pro) Signaling Pathway in Vibrio vulnificus
por: Park, Na-Young, et al.
Publicado: (2019)

Novel RHD allele with c.333C>G change predicted to encode p.Phe111Leu
por: Alluin, Gauthier, et al.
Publicado: (2022)

The fungal UPR: A regulatory hub for virulence traits in the mold pathogen Aspergillus fumigatus
por: Krishnan, Karthik, et al.
Publicado: (2014)

Distribution and dissemination of the Val1016Ile and Phe1534Cys Kdr mutations in Aedes aegypti Brazilian natural populations
por: Linss, Jutta Gerlinde Birggitt, et al.
Publicado: (2014)

The mechanism (Phe362Tyr mutation) behind resistance in Lepeophtheirus salmonis pre-dates organophosphate use in salmon farming
por: Kaur, Kiranpreet, et al.
Publicado: (2017)

Peptide Probes with Aromatic Residues Tyr and Phe at the X Position Show High Specificity for Targeting Denatured Collagen in Tissues
por: Wei, Wenyu, et al.
Publicado: (2020)

Case analysis of early-onset Alzheimer's disease associated with TBK1 p.Tyr235Phe gene mutation
por: Li, Pan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_j26j264iqms7l239p3mnns09ep