Quantitative estimation and correlation of serum albumin levels in clinically healthy subjects and chronic periodontitis patients

AIM: The aim of this study was to evaluate the relationship between periodontal disease and general health status in adults using the serum albumin concentration. MATERIALS AND METHODS: A total of 100 patients of both genders with age range of 40 to 70 years were included in the study. Patients were divided into the following two groups: clinically healthy subjects and patients with periodontitis, that is, loss of attachment ≥5 mm. Dental examinations were carried out at baseline and clinical attachment levels were measured at four sites. Serum albumin concentration was estimated by bromocresol green albumin method. RESULTS: The mean serum albumin levels for Group I was 4.47 g/dl with standard deviation (SD) of 0.276 and for Group II, the mean value of serum albumin was 4.61 g/dl with SD of 0.273. Using Student's unpaired ′t′ test, the difference between the serum albumin levels in Group I and Group II were found to be statistically significant (P=0.020). The mean body mass index values for Group I was 22.63 with a SD of 3.85, whereas the same for Group II was 22.23 with a SD of 4.21, which were on comparison, found to be nonsignificant (P=0.462). CONCLUSION: The findings of the clinical trial suggest an inverse relationship between the serum albumin concentration and chronic periodontal disease.