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Identification of a novel temperature sensitive promoter in cho cells
BACKGROUND: The Chinese hamster ovary (CHO) expression system is the leading production platform for manufacturing biopharmaceuticals for the treatment of numerous human diseases. Efforts to optimize the production process also include the genetic construct encoding the therapeutic gene. Here we rep...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118111/ https://www.ncbi.nlm.nih.gov/pubmed/21569433 http://dx.doi.org/10.1186/1472-6750-11-51 |