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Identification of a novel temperature sensitive promoter in cho cells

BACKGROUND: The Chinese hamster ovary (CHO) expression system is the leading production platform for manufacturing biopharmaceuticals for the treatment of numerous human diseases. Efforts to optimize the production process also include the genetic construct encoding the therapeutic gene. Here we rep...

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Detalles Bibliográficos
Autores principales:	Thaisuchat, Haruthai, Baumann, Martina, Pontiller, Jens, Hesse, Friedemann, Ernst, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118111/ https://www.ncbi.nlm.nih.gov/pubmed/21569433 http://dx.doi.org/10.1186/1472-6750-11-51

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