Thymic plasmacytoid dendritic cells are susceptible to productive HIV-1 infection and efficiently transfer R5 HIV-1 to thymocytes in vitro

BACKGROUND: HIV-1 infection of the thymus contributes to the defective regeneration and loss of CD4(+ )T cells in HIV-1-infected individuals. As thymic dendritic cells (DC) are permissive to infection by HIV-1, we examined the ability of thymic DC to enhance infection of thymocytes which may contrib...

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Detalles Bibliográficos
Autores principales: Evans, Vanessa A, Lal, Luxshimi, Akkina, Ramesh, Solomon, Ajantha, Wright, Edwina, Lewin, Sharon R, Cameron, Paul U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118182/
https://www.ncbi.nlm.nih.gov/pubmed/21639903
http://dx.doi.org/10.1186/1742-4690-8-43

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