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Use of cytokine immunotherapy to block CNS demyelination induced by a recombinant HSV-1 expressing IL-2

We previously have described a model of MS in which constitutive expression of murine IL-2 by HSV-1 (HSV-IL-2) causes CNS demyelination in different strains of mice (Zandian et al 2009, IOVS, 50:3275). In the current study, we investigated whether this HSV-IL-2-induced demyelination can be blocked u...

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Detalles Bibliográficos
Autores principales:	Zandian, Mandana, Mott, Kevin R., Allen, Sariah J, Dumitrascu, Oana, Kuo, Jane Z, Ghiasi, Homayon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118258/ https://www.ncbi.nlm.nih.gov/pubmed/21412284 http://dx.doi.org/10.1038/gt.2011.32

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