Lentiviral vector-mediated stable expression of sTNFR-Fc in human macrophage and neuronal cells as a potential therapy for neuroAIDS

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) infection frequently causes neurologic disease, which is the result of viral replication and activation of macrophages and microglia in the CNS, and subsequent secretion of high levels of neurotoxic products, including tumor necrosis factor-α (...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Shengbo, Wu, Chengxiang, Yang, Yongbo, Sniderhan, Lynn F, Maggirwar, Sanjay B, Dewhurst, Stephen, Lu, Yuanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118348/
https://www.ncbi.nlm.nih.gov/pubmed/21569583
http://dx.doi.org/10.1186/1742-2094-8-48

Ejemplares similares

Ejemplares similares