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ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair

Rad50 ABC-ATPase complex with Mre11 nuclease is essential for dsDNA break repair, telomere maintenance, and ataxia telangiectasia mutated kinase checkpoint signaling. How Rad50 affects Mre11 functions, and how ABC-ATPases communicate nucleotide binding and ligand states across long distances and amo...

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Detalles Bibliográficos
Autores principales:	Williams, Gareth J., Williams, R. Scott, Williams, Jessica S., Moncalian, Gabriel, Arvai, Andy, Limbo, Oliver, Guenther, Grant, SilDas, Soumita, Hammel, Michal, Russell, Paul, Tainer, John A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118400/ https://www.ncbi.nlm.nih.gov/pubmed/21441914 http://dx.doi.org/10.1038/nsmb.2038

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