Cargando…

The Effect of Cordycepin on Steroidogenesis and Apoptosis in MA-10 Mouse Leydig Tumor Cells

Cordycepin is a natural pure compound extracted from Cordyceps sinensis (CS). We have demonstrated that CS stimulates steroidogenesis in primary mouse Leydig cell and activates apoptosis in MA-10 mouse Leydig tumor cells. It is highly possible that cordycepin is the main component in CS modulating L...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Bo-Syong, Lin, Chun-Yu, Huang, Bu-Miin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118483/ https://www.ncbi.nlm.nih.gov/pubmed/21716681 http://dx.doi.org/10.1155/2011/750468

Ejemplares similares

Apoptotic effect of cordycepin combined with cisplatin and/or paclitaxel on MA-10 mouse Leydig tumor cells
por: Kang, Fu-Chi, et al.
Publicado: (2015)

Cordycepin Induced MA-10 Mouse Leydig Tumor Cell Apoptosis through Caspase-9 Pathway
por: Jen, Chun-Yi, et al.
Publicado: (2011)

Cordycepin induced MA-10 mouse Leydig tumor cell apoptosis by regulating p38 MAPKs and PI3K/AKT signaling pathways
por: Pan, Bo-Syong, et al.
Publicado: (2015)

Cordycepin inhibits ERK pathway to suppress FGF9-induced tumorigenesis with MA-10 mouse Leydig tumor cells
por: Chen, Li-Ching, et al.
Publicado: (2023)

Midazolam induces apoptosis in MA-10 mouse Leydig tumor cells through caspase activation and the involvement of MAPK signaling pathway
por: So, Edmund Cheung, et al.
Publicado: (2014)

Midazolam regulated caspase pathway, endoplasmic reticulum stress, autophagy, and cell cycle to induce apoptosis in MA-10 mouse Leydig tumor cells
por: So, Edmund Cheung, et al.
Publicado: (2016)

Arsenic compounds activate MAPK and inhibit Akt pathways to induce apoptosis in MA‐10 mouse Leydig tumor cells
por: Juan, Wei‐Sheng, et al.
Publicado: (2022)

Cordycepin‐induced unfolded protein response‐dependent cell death, and AKT/MAPK‐mediated drug resistance in mouse testicular tumor cells
por: Chang, Ming‐Min, et al.
Publicado: (2019)

Dynamic Remodeling of Membranes and Their Lipids during Acute Hormone-Induced Steroidogenesis in MA-10 Mouse Leydig Tumor Cells
por: Venugopal, Sathvika, et al.
Publicado: (2021)

Functional study of Cordyceps sinensis and cordycepin in male reproduction: A review
por: Chen, Yung-Chia, et al.
Publicado: (2016)

Fibroblast Growth Factor 9 Activates Akt and MAPK Pathways to Stimulate Steroidogenesis in Mouse Leydig Cells
por: Lai, Meng-Shao, et al.
Publicado: (2014)

Effects of the Yangjing Capsule Extract on Steroidogenesis and Apoptosis in Mouse Leydig Cells
por: Sun, Dalin, et al.
Publicado: (2012)

Steroidogenesis and early response gene expression in MA-10 Leydig tumor cells following heterologous receptor down-regulation and cellular desensitization
por: Chen, Tsuey-Ming, et al.
Publicado: (2016)

Midazolam activates caspase, MAPKs and endoplasmic reticulum stress pathways, and inhibits cell cycle and Akt pathway, to induce apoptosis in TM3 mouse Leydig progenitor cells
por: Kang, Fu-Chi, et al.
Publicado: (2018)

Comprehensive and Quantitative Analysis of the Changes in Proteomic and Phosphoproteomic Profiles during Stimulation and Repression of Steroidogenesis in MA-10 Leydig Cells †
por: Demmouche, Zoheir B., et al.
Publicado: (2022)

Fatty acids suppress the steroidogenesis of the MA-10 mouse Leydig cell line by downregulating CYP11A1 and inhibiting late-stage autophagy
por: Huang, Chien, et al.
Publicado: (2021)

Cordycepin enhances cisplatin apoptotic effect through caspase/MAPK pathways in human head and neck tumor cells
por: Chen, Ying-Hui, et al.
Publicado: (2013)

Mitochondrial TSPO Deficiency Triggers Retrograde Signaling in MA-10 Mouse Tumor Leydig Cells
por: Fan, Jinjiang, et al.
Publicado: (2020)

Effects of Etomidate on the Steroidogenesis of Rat Immature Leydig Cells
por: Liu, Hua-Cheng, et al.
Publicado: (2015)

Slit/Robo signaling regulates Leydig cell steroidogenesis
por: Martinot, Emmanuelle, et al.
Publicado: (2021)

Molecular Mechanism of Isocupressic Acid Supresses MA-10 Cell Steroidogenesis
por: Tsui, Kuan-Hao, et al.
Publicado: (2012)

FGF9/FGFR2 increase cell proliferation by activating ERK1/2, Rb/E2F1, and cell cycle pathways in mouse Leydig tumor cells
por: Chang, Ming‐Min, et al.
Publicado: (2018)

BMI1 promotes steroidogenesis through maintaining redox homeostasis in mouse MLTC-1 and primary Leydig cells
por: Gao, Tingting, et al.
Publicado: (2020)

Astaxanthin Protects Steroidogenesis from Hydrogen Peroxide-Induced Oxidative Stress in Mouse Leydig Cells
por: Wang, Jyun-Yuan, et al.
Publicado: (2015)

Specific Transcriptomic Signatures and Dual Regulation of Steroidogenesis Between Fetal and Adult Mouse Leydig Cells
por: Sararols, Pauline, et al.
Publicado: (2021)

Jagged1 intracellular domain modulates steroidogenesis in testicular Leydig cells
por: Kumar, Sudeep, et al.
Publicado: (2020)

Prohibitin-1 plays a regulatory role in Leydig cell steroidogenesis
por: Bassi, Geetika, et al.
Publicado: (2022)

The Role of Autophagy in Anti-Cancer and Health Promoting Effects of Cordycepin
por: Chen, Yu-Ying, et al.
Publicado: (2021)

Gigantol Improves Cholesterol Metabolism and Progesterone Biosynthesis in MA-10 Leydig Cells
por: Basque, Audrey, et al.
Publicado: (2021)

Cordycepin Induces Apoptosis through JNK-Mediated Caspase Activation in Human OEC-M1 Oral Cancer Cells
por: Tung, Kuo-Lung, et al.
Publicado: (2022)

A Testis-Specific Long Noncoding RNA, Start, Is a Regulator of Steroidogenesis in Mouse Leydig Cells
por: Otsuka, Kai, et al.
Publicado: (2021)

Hormone-Dependent Expression of a Steroidogenic Acute Regulatory Protein Natural Antisense Transcript in MA-10 Mouse Tumor Leydig Cells
por: Castillo, Ana Fernanda, et al.
Publicado: (2011)

Cordycepin Enhances Radiosensitivity in Oral Squamous Carcinoma Cells by Inducing Autophagy and Apoptosis Through Cell Cycle Arrest
por: Ho, Sheng-Yow, et al.
Publicado: (2019)

Comparison of the Effects of Dibutyl and Monobutyl Phthalates on the Steroidogenesis of Rat Immature Leydig Cells
por: Li, Linxi, et al.
Publicado: (2016)

The in vitro modulation of steroidogenesis by inflammatory cytokines and insulin in TM3 Leydig cells
por: Leisegang, Kristian, et al.
Publicado: (2018)

Functional metabolite reserves and lipid homeostasis revealed by the MA-10 Leydig cell metabolome
por: Koganti, Prasanthi P, et al.
Publicado: (2022)

A 35-bp Conserved Region Is Crucial for Insl3 Promoter Activity in Mouse MA-10 Leydig Cells
por: Giner, Xavier C., et al.
Publicado: (2022)

Time-Course Changes of Steroidogenic Gene Expression and Steroidogenesis of Rat Leydig Cells after Acute Immobilization Stress
por: Lin, Han, et al.
Publicado: (2014)

Anti-Cancer Effect of Cordycepin on FGF9-Induced Testicular Tumorigenesis
por: Chang, Ming-Min, et al.
Publicado: (2020)

Calretinin Participates in Regulating Steroidogenesis by PLC-Ca(2+)-PKC Pathway in Leydig Cells
por: Xu, Wendan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_h5epl29qdm1vjprgqn1ndo8rqv