Tyrosine Kinase Syk Non-Enzymatic Inhibitors and Potential Anti-Allergic Drug-Like Compounds Discovered by Virtual and In Vitro Screening

In the past decade, the spleen tyrosine kinase (Syk) has shown a high potential for the discovery of new treatments for inflammatory and autoimmune disorders. Pharmacological inhibitors of Syk catalytic site bearing therapeutic potential have been developed, with however limited specificity towards...

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Detalles Bibliográficos
Autores principales: Villoutreix, Bruno O., Laconde, Guillaume, Lagorce, David, Martineau, Pierre, Miteva, Maria A., Dariavach, Piona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118801/
https://www.ncbi.nlm.nih.gov/pubmed/21701581
http://dx.doi.org/10.1371/journal.pone.0021117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118801/
https://www.ncbi.nlm.nih.gov/pubmed/21701581
http://dx.doi.org/10.1371/journal.pone.0021117

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